Evaluation of Prosthetic Implant Degradation

Orthopedic Prostheses

December 2011

Joint replacement is a successful treatment for advanced joint disease, and implantation of orthopedic prosthetic devices contributes to quality of life. Following the initial launch of metal-on-polyethylene bearings, improved bearing surfaces made of ceramic-on-ceramic and metal-on-metal came into the marketplace to enhance the durability for younger and more active individuals. These newer devices were expected to stand up better to constant wear. Metal-on-metal hip replacements have the advantage of increased toughness, decreased wear, and reduced risk of dislocation because of the larger bearing surface.

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Jump to section:

• Introduction
• Orthopedic Prostheses
• Background
• Patient Workup
• Issues of Concern
• Metal-on-Metal Wear-Induced Tissue Necrosis
• Metal-on-Metal Wear-Induced Tissue Necrosis
• Effect of Metallosis
• Initial Conclusions
• Interpretive Values
• Are These Concentrations Toxic?
• Are These Concentrations Toxic?
• Specimen Collection
• Metal-Free Blood Tubes
• Summary
• References/Additional Reading
• Questions?
• Disclosure (Dr. Sierra)
• Disclosure (Dr. Moyer)