Mobile Site ›

The Classic Myeloproliferative Neoplasms

Optimizing Laboratory Testing for Hematologic Disorders Series



Summary

Slide 28

October 2011

In summary, JAK2 V617F results are similar in peripheral blood and bone marrow. JAK2 exon 12 and MPL exon 10 sequencing studies frequently are not needed and should not be ordered without knowing results of the JAK2 V617F study. In particular, the JAK2 exon 12 sequencing studies should not be ordered unless the CBC and serum erythropoietin are suggestive of PV, and MPL exon 10 sequencing should not be ordered unless the bone marrow findings are suggestive, but not diagnostic, of a myeloproliferative neoplasm.

Summary

 


Jump to section:


Key