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The Classic Myeloproliferative Neoplasms

Optimizing Laboratory Testing for Hematologic Disorders Series

MPL Exon 10 Sequencing

Slide 25

October 2011

We looked back at 60 Mayo Clinic patients who had MPL exon 10 sequencing done and noted that only 22, or 37%, appeared to be appropriately ordered, ie, those who had negative V617F and had borderline bone marrow features as described on the previous slide. 38 were inappropriately ordered as they had no V617F testing done, had already been identified has having the V617F mutation, had diagnostic bone marrow features, ie, definite myeloproliferative neoplasm, or were normal bone marrows with no features of a myeloproliferative disorder.

MPL Exon 10 Sequencing


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