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The Classic Myeloproliferative Neoplasms

Optimizing Laboratory Testing for Hematologic Disorders Series

MPL Exon 10 Sequencing: When Not to Use

Slide 24

October 2011

There are 3 scenarios in which exon 10 sequencing should not be done. It’s certainly not useful in classic myeloproliferative neoplasms that can be diagnosed by bone marrow morphologic features. It’s not useful when JAK2 V617F studies are positive, and it’s not useful in patients who are likely to have PV on the basis of their CBC and serum erythropoietin findings.

Exon 10 Sequencing: When Not to Use


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