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The Classic Myeloproliferative Neoplasms

Optimizing Laboratory Testing for Hematologic Disorders Series

Microscopic Examination: Biopsy

Slide 13

October 2011

We looked back at 267 Mayo Clinic patients in whom both peripheral blood and bone marrow studies for JAK2 V617F were done. As you can see, 98.5% of those patients had concordant results between peripheral blood and bone marrow with approximately one-half being positive and one-half being negative. Four out of the 267 showed discrepant results: 2 with a positive bone marrow and negative peripheral blood, and 2 the converse, having a positive peripheral blood and negative bone marrow.

JAK2 V617F


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