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Fecal Occult Blood Testing

Which Test?

CRC Screening by FOBTs

Slide 18

October 2011

So, let’s compare fecal blood test features for the application of colorectal cancer screening. Both sensitive guaiac and FIT tests achieve moderate sensitivity for cancer of >60% but FIT does so, as I mentioned previously, with a single test per patient screen. No test detected advanced adenomas well. FIT generally yields not only the highest sensitivity, but the highest specificities, and uniquely requires no diet or medication restriction. Finally, because of its numerical reporting, the result comes out objectively. Because HemoQuant detects upper GI bleeding so well, it yields lower specificity for colorectal cancer screening and is not recommended for this application.

CRC Screening by FOBTs


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