Fecal Occult Blood Testing

Evaluation of Fecal Immunochemical Testing (FIT) Assays

October 2011

We recently completed a simple comparison of a quantitative and a qualitative FIT test. The former is semi-automated and is objectively reported as a number and the later reported subjectively by presence of a colored band on the immuno-strip.

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Evaluation of FIT Assays

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Jump to section:

• Introduction
• Occult Gastrointestinal (GI) Bleeding: Definition
• Quantity of GI Bleeding Required to "See" Blood in Stool
• Fecal Occult Blood Tests
• Why Detect Occult GI Bleeding?
• Causes of Fe Deficiency in Industrialized Countries (Average %)
• Causes of Occult GI Bleeding
• Fecal Detection of Ingested Blood
• Iron Deficiency or Anemia: Which Test?
• CRC Screening: Target Lesions
• Occult Bleeding From Colorectal Cancer
• Fecal Blood Testing for Colorectal Cancer (CRC)
• Microscopic Examination: Biopsy
• FOBT Screening
• Stool Test Detection of CRN in Screen Setting
• Laboratory Testing vs Office Digital Rectal Exam (DRE)
• Evaluation of Fecal Immunochemical Testing (FIT) Assays
• FIT Specificity
• CRC Screening by FOBTs
• CRC Screening Guidelines*
• CRC Screening: Which Fecal Blood Test?
• Soft Indications for FOBT Use?
• Fecal Occult Blood Tests Summary
• Mayo Medical Laboratories Tests
• Questions?
• Disclosures