Fecal Occult Blood Testing
An issue that has come up historically regards use of digital rectal exam for clinical diagnosis or screening. Based on results from multiple studies, this practice is now discouraged by professional societies and in national screening guidelines. In one such study, Hemoccult testing from a single digital rectal exam was compared to 3 stools tested in the laboratory. As shown, digital rectal exam detected only 5%, which was about the same rate as over all false-positivity rate versus nearly 30% by laboratory testing. Furthermore, quality is difficult to control in the office setting due to monitoring of outdated kits, wide variation in interpretation of results, and inconsistent documentation that fecal blood test was checked. So, one could argue that digital rectal examination as an approach to fecal blood testing has little value.
Laboratory Testing vs Office DRE
Jump to section:
- Occult Gastrointestinal (GI) Bleeding: Definition
- Quantity of GI Bleeding Required to "See" Blood in Stool
- Fecal Occult Blood Tests
- Why Detect Occult GI Bleeding?
- Causes of Fe Deficiency in Industrialized Countries (Average %)
- Causes of Occult GI Bleeding
- Fecal Detection of Ingested Blood
- Iron Deficiency or Anemia: Which Test?
- CRC Screening: Target Lesions
- Occult Bleeding From Colorectal Cancer
- Fecal Blood Testing for Colorectal Cancer (CRC)
- FOBT Screening
- Stool Test Detection of CRN in Screen Setting
- Laboratory Testing vs Office Digital Rectal Exam (DRE)
- Evaluation of Fecal Immunochemical Testing (FIT) Assays
- FIT Specificity
- CRC Screening by FOBTs
- CRC Screening Guidelines*
- CRC Screening: Which Fecal Blood Test?
- Soft Indications for FOBT Use?
- Fecal Occult Blood Tests Summary
- Mayo Medical Laboratories Tests