Fecal Occult Blood Testing

FOBT Screening

October 2011

To underscore this point, a meta-analysis of the 4 randomized controlled trials with Hemoccult screening showed only a modest reduction in cancer mortality (about 14% overall over 12 to 18 years) but no effect on cancer incidence. This collective finding would be consistent with a test that detects some early stage cancers but few precancers. Health care providers and their patients who choose to use fecal blood testing as an approach to colorectal cancer screening should be mindful of these reported outcomes.

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FOBT Screening

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Jump to section:

• Introduction
• Occult Gastrointestinal (GI) Bleeding: Definition
• Quantity of GI Bleeding Required to "See" Blood in Stool
• Fecal Occult Blood Tests
• Why Detect Occult GI Bleeding?
• Causes of Fe Deficiency in Industrialized Countries (Average %)
• Causes of Occult GI Bleeding
• Fecal Detection of Ingested Blood
• Iron Deficiency or Anemia: Which Test?
• CRC Screening: Target Lesions
• Occult Bleeding From Colorectal Cancer
• Fecal Blood Testing for Colorectal Cancer (CRC)
• FOBT Screening
• Stool Test Detection of CRN in Screen Setting
• Laboratory Testing vs Office Digital Rectal Exam (DRE)
• Evaluation of Fecal Immunochemical Testing (FIT) Assays
• FIT Specificity
• CRC Screening by FOBTs
• CRC Screening Guidelines*
• CRC Screening: Which Fecal Blood Test?
• Soft Indications for FOBT Use?
• Fecal Occult Blood Tests Summary
• Mayo Medical Laboratories Tests
• Questions?
• Disclosures