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Fecal Occult Blood Testing

Which Test?



Fecal Detection of Ingested Blood

Slide 8

October 2011

As mentioned earlier, detection of upper GI bleeding differs dramatically by type of fecal blood test used. Based on recovery of ingested blood (simulating upper GI bleeding), only the HemoQuant test proves to be reliable. With simulated bleeding rates of over 15 mL/day (3 times the amount required to produce iron deficiency or anemia), FIT remains negative. In contrast, HemoQuant detected 100% of that level of bleeding. Based on correlation with HemoQuant tests in patients, >150 mL blood/day is required for upper GI bleeding to be reliably detected by the FIT test. As upper GI bleeding is the most common cause of iron deficiency, it is especially important that the tool used is capable of sensitive detection of upper GI bleeding.

Fecal Detection of Ingested Blood

 


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