The Role of the Laboratory in the Diagnosis of Rheumatoid Arthritis
1987 Classification Criteria for Rheumatoid Arthritis
August 2011
In 1987, the American College of Rheumatology established a set of classification criteria for rheumatoid arthritis. These criteria focused heavily on clinical symptoms.
The criteria included morning stiffness that lasted longer than 1 hour and arthritis of 3 or more joints, particularly the hand joints , that was accompanied by inflammation and swelling. In particular, symmetric arthritis was included as an important indicator of rheumatoid arthritis.
The presence of nodules was also an indication of the disease, as were radiographic changes that indicated the presence of erosions or boney decalcification.
The only laboratory test that was part of these criteria was rheumatoid factor.
Using these criteria, it was suggested that, if 4 out of the 7 features were present, then the patient could be classified as having rheumatoid arthritis. Although very useful, these criteria were limited in their ability to classify patients with early disease.
1987 Classification Criteria for RA |
Jump to section:
- Introduction
- Introduction to Rheumatoid Arthritis
- Risk Factors Associated with Development of Rheumatoid Arthritis
- Clinical Symptoms of Rheumatoid Arthritis
- 1987 Classification Criteria for Rheumatoid Arthritis
- 2010 Classification Criteria for Rheumatoid Arthritis
- Laboratory Evaluation of Patient with RA
- Utility of Rheumatoid Factor
- Discovery of Anti-Citrulline Antibodies
- Enzymatic Process of Citrullination
- Diagnostic Performance of Anti-Citrulline Antibodies
- Development of Clinical Assays for Anti-Citrullinated Protein Antibodies
- Development of Clinical Assays for Anti-Citrullinated Protein Antibodies
- Sensitivity and Specificity Comparison Anti-CCP and RF
- Summary
- Questions?
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