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Use of Cystatin C to Assess Kidney Function


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Slide 27

August 2011

In conclusion, blood levels of cystatin C reflect GFR better than blood levels of creatinine alone. However, equations that use creatinine and demographics to predict an estimated GFR perform about as well as cystatin C alone. Elevated cystatin C levels identify patients at greater risk of CKD progression and early death, largely from cardiovascular morbidity. And finally, in the hospital setting cystatin C levels may be a better indicator of GFR, and levels of cystatin C may increase earlier than creatinine among patients that experience acute kidney injury. Thank you.



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