Mobile Site ›

Use of Cystatin C to Assess Kidney Function



Subscribe

Receive notification when new Hot Topics are published:

Creatinine as a Marker of GFR: It Works But...

Slide 10

August 2011

This slide clearly demonstrates both the utility and problems with using serum creatinine alone to estimate GFR. Serum creatinine numbers are plotted against measured GFR in a large number of individuals with and without kidney disease. In general, it is quite true that serum creatinine increases as GFR falls. However, creatinine does not increase very much until GFR is well below 60 mL per minute per 1.73 m2. Such a person already would have stage 3 chronic kidney disease.  The dotted line corresponds to a serum creatinine of 1.2 milligrams per deciliter, the upper limit of the reference range. Such a serum creatinine could correspond to a GFR as low as 25 or as high as 130 mL per minute per 1.73 m2.

Creatinine as a Marker of GFR: It Works But...

 


Jump to section:


Key