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Use of Cystatin C to Assess Kidney Function



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Stages of Chronic Kidney Disease

Slide 7

August 2011

Patients with chronic kidney disease are now classified into 5 stages. Persons in stage 1 or 2 have good GFR but other evidence of kidney damage. Persons in stage 3 CKD have moderately reduced GFR, less than 60 mL per minute per 1.73 m2. In general, persons in stage 3 are at risk for further loss of kidney function, although this risk is quite variable. Therefore, it is important to intervene and modify all possible risk factors to reduce this risk to the greatest extent possible. Persons in stage 4 CKD have a GFR less than 30 mL per minute per 1.73 m2. Studies suggest such individuals are at high risk for complications of chronic kidney disease, such as anemia and bone disease. Furthermore, cardiovascular complications are very high in persons with stage 4 CKD. Therefore, it is important to identify these persons in order to treat their complications of kidney disease and modify all possible cardiovascular risk factors. Finally, persons with stage 5 CKD have a GFR less than 15 mL per minute per 1.73 m2. This is typically in the threshold where persons are symptomatic and need to start on a renal replacement therapy, such as dialysis or kidney transplantation.

Stages of Chronic Kidney Disease

 


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