Zygomycosis and the Joplin Tornado

Large Pauciseptate Hyphae—H&E Stain

July 2011

This is an example of what you would see in a biopsy. This is an H&E stained slide that you would look at for tissue morphology but in this case, you see where the arrow is, there are large hyphae that are present in there that really show very little evidence of septations. Although, you can see a couple of areas where there are septations. And this is what is called pauciseptate hyphae. There are not regular septations throughout the whole length of the hyphal strand and a lot of times these Zygomycetes have fractured pieces of hyphae within the tissue rather than very long pieces.

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Jump to section:

• Introduction
• Tragedy in Joplin
• Unsuspected Fungal Infection Infects Some Joplin Residents
• Zygomycosis
• The Zygomycetes
• The Zygomycetes
• Pauciseptate Hyphae
• Zygomycetes: Basic Structures
• Basic Structures
• Rhizopus Species
• Lichtheimia (Absidia) Species
• Lichtheimia Species
• Mucor Species
• Cunninghamella Species
• Apophysomyces elegans
• Apophysomyces elegans
• Apophysomyces elegans
• Apophysomyces elegans
• Apophysomyces elegans
• Diagnosis of Zygomycosis
• Large Pauciseptate Hyphae—H&E Stain
• Unstained Hyphal Fragment On GMS-Stained Tissue
• Vascular Invasion By Hyphae
• Large Pauciseptate Hyphae—Calcofluor White
• Video Credits
• Questions?