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Von Willebrand Disease (VWD)
Part 2: NHLBI Diagnosis Guidelines

Laboratory Recommendations

von Willebrand Disease Profile

Slide 26

June 2011

If VWF antigen and latex activity are equal to or higher than 55 U/dL, and the activity over antigen ratio is above 0.8, no further testing will be performed as highlighted by the green lines and arrows. But keep in mind that the sensitivity of detecting an acquired VWF abnormality due to subtle losses of highest molecular weight multimers is 90%.

von Willebrand Disease Profile


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