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Von Willebrand Disease (VWD)
Part 2: NHLBI Diagnosis Guidelines

Laboratory Recommendations



Sensitivity and Specificity of the Screening Panel

Slide 23

June 2011

By using this criteria, we screened the same 492 samples; we can catch 100% congential VWD samples and 83% of acquired VWF abnormalities due to subtle losses of highest molecular weight multimers. The specificity is 92% which can be translated into a 92% reduction of VWF ristocetin cofactor activity testing volume of the potentially normal samples.

Sensitivity and Specificity of the Screening Panel

 


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