Von Willebrand Disease (VWD)
Part 1: NHLBI Diagnosis Guidelines

VWD NHLBI Guidelines (2008)

May 2011

In summary, the patient history assessment and focused physical examination are the first steps in the evaluation of bleeding symptoms and risk, and for the evaluation of the possible presence of a bleeding disorder such as VWD. Physical examination should include evaluation for evidence of a bleeding disorder, or other causes or risks of increased bleeding. Increasing numbers of positive responses to questions about bleeding, and abnormal findings on physical examination, increase the probability of a bleeding disorder, including possible VWD.

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VWD NHLBI Guidelines (2008)

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Jump to section:

• Introduction
• Objectives — Part 1
• VWF Biology
• VWF and Normal Hemostasis¹
• VWF Structure and Domains¹
• VWD Classification — ISTH^1,2
• VWD: Prevalence, Inheritance, Symptoms
• Disorders Pathophysiologically Associated with Acquired von Willebrand Syndrome (AVWS)³
• VWD NHLBI Guidelines — Background
• NHLBI VWD Expert Panel
• Methodology
• Methodology
• Overall Outcome / Results
• Initial Clinical Evaluation for VWD or Other Bleeding Disorders¹
• Common Bleeding Symptoms of Healthy Persons vs. VWD Patients¹
• VWD NHLBI Guidelines (2008)¹Initial Patient Evaluation — History⁴
• VWD NHLBI Guidelines (2008) Initial Patient Evaluation — History
• Initial Patient Evaluation — History
• VWD NHLBI Guidelines (2008)
• References
• Questions?