Von Willebrand Disease (VWD)
Part 1: NHLBI Diagnosis Guidelines

Common Bleeding Symptoms of Healthy Persons vs. VWD Patients¹

May 2011

This slide, based on Table 7 from the NHLBI VWD Guidelines, illustrates a variety of bleeding symptoms (eg, epistaxis, menorrhagia, ecchymoses, bleeding from wounds or dental extractions or surgical procedures, etc) — and demonstrates that, individually such bleeding symptoms commonly occur in apparently normal persons, with prevalences up to 50% or higher. However, the prevalences and types and numbers of episodes of these symptoms are typically increased in persons with VWD — who may also have a family history suggesting a hereditary bleeding disorder.

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Common Bleeding Symptoms1

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Jump to section:

• Introduction
• Objectives — Part 1
• VWF Biology
• VWF and Normal Hemostasis¹
• VWF Structure and Domains¹
• VWD Classification — ISTH^1,2
• VWD: Prevalence, Inheritance, Symptoms
• Disorders Pathophysiologically Associated with Acquired von Willebrand Syndrome (AVWS)³
• VWD NHLBI Guidelines — Background
• NHLBI VWD Expert Panel
• Methodology
• Methodology
• Overall Outcome / Results
• Initial Clinical Evaluation for VWD or Other Bleeding Disorders¹
• Common Bleeding Symptoms of Healthy Persons vs. VWD Patients¹
• VWD NHLBI Guidelines (2008)¹Initial Patient Evaluation — History⁴
• VWD NHLBI Guidelines (2008) Initial Patient Evaluation — History
• Initial Patient Evaluation — History
• VWD NHLBI Guidelines (2008)
• References
• Questions?