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Serologic Testing for Syphilis


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Interpretation and Follow-up

Slide 15

April 2011

In the second scenario, a patient presents with an unknown history of syphilis, and the results of both the screening treponemal test and the RPR are positive. In this situation, a second treponemal test is not required, and we would interpret these results as either untreated syphilis, or recently treated syphilis. For follow-up, I would refer you to the CDC website for up-to-date treatment guidelines and also recommendations on further testing, which generally includes following RPR titers to demonstrate a response to therapy.

Interpretation and Follow-up


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