Serologic Testing for Syphilis
Interpretation and Follow-up
April 2011
In the second scenario, a patient presents with an unknown history of syphilis, and the results of both the screening treponemal test and the RPR are positive. In this situation, a second treponemal test is not required, and we would interpret these results as either untreated syphilis, or recently treated syphilis. For follow-up, I would refer you to the CDC website for up-to-date treatment guidelines and also recommendations on further testing, which generally includes following RPR titers to demonstrate a response to therapy.
Interpretation and Follow-up |
Jump to section:
- Introduction
- Presentation Outline
- Syphilis — The "Great Imitator"
- Diagnosis: Laboratory Testing
- Diagnosis: Nontreponemal Serology Tests
- Diagnosis: Treponemal Serology Tests
- Diagnosis: Traditional Algorithm
- Diagnosis: Traditional Algorithm
- Syphilis — Incidence
- Syphilis — Incidence
- Diagnosis: Contemporary Algorithm
- Diagnosis: Contemporary Algorithm
- Diagnosis: Proposed Algorithm with Treponemal Screening Test
- Interpretation and Follow-up
- Interpretation and Follow-up
- Interpretation and Follow-up
- Interpretation and Follow-up
- Interpretation and Follow-up
- Conclusions
- Conclusions
- Questions?


