Serologic Testing for Syphilis

Interpretation and Follow-up

April 2011

In the first scenario, you’re seeing a patient with no history, or an unknown history, of syphilis. The result of the screening treponemal test is negative, so no additional testing is required. We interpret this result as “no serologic evidence of syphilis” and in most situations no further testing is required, unless clinically indicated, such as a suspected early syphilis infection.

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Interpretation and Follow-up

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Jump to section:

• Introduction
• Presentation Outline
• Syphilis — The "Great Imitator"
• Diagnosis: Laboratory Testing
• Diagnosis: Nontreponemal Serology Tests
• Diagnosis: Treponemal Serology Tests
• Diagnosis: Traditional Algorithm
• Diagnosis: Traditional Algorithm
• Syphilis — Incidence
• Syphilis — Incidence
• Diagnosis: Contemporary Algorithm
• Diagnosis: Contemporary Algorithm
• Diagnosis: Proposed Algorithm with Treponemal Screening Test
• Interpretation and Follow-up
• Interpretation and Follow-up
• Interpretation and Follow-up
• Interpretation and Follow-up
• Interpretation and Follow-up
• Conclusions
• Conclusions
• Questions?