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Serologic Testing for Syphilis


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Diagnosis: Traditional Algorithm

Slide 8

April 2011

As I mentioned, this traditional algorithm has been in place for decades and has several advantages, including the fact that it is a reliable method, especially in high-prevalence settings. In addition, this algorithm utilizes a rapid, inexpensive screening method that is economical and easily implemented in most hospitals and small clinics. However, this approach has limitations, including a low throughput and subjective interpretation of the screening RPR results. This subjectivity, along with the fact that RPR detects mainly non-specific antibodies can translate into higher rates of false-positive results, especially in low-incidence settings.

Diagnosis: Traditional Algorithm


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