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Serologic Testing for Syphilis


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Diagnosis: Treponemal Serology Tests

Slide 6

April 2011

The second class of syphilis serology tests is the treponemal assays, which are designed to detect antibodies against specific antigens from Treponema pallidum. Examples include fluorescent treponemal antibody, or FTA, Treponema pallidum particle agglutination, or TP-PA, and newer generation assays such as enzyme immunoassays. Although these tests are typically more specific than nontreponemal assays, they will remain positive for years despite treatment, and this has significant implications that we’ll discuss later in the presentation.

Diagnosis: Treponemal Serology Tests


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