Circulating Tumor Cells and the CellSearch Assay
The Future of CTC
April 2011
We hope that we have demonstrated the important role of CTC analysis in the management of patients with metastatic breast, colorectal, and prostate cancer. Additional studies are being performed to examine the clinical utility of the CellSearch assay for other tumors such as urothelial cancer, lung cancer, and melanoma. Possibly most importantly are additional studies to determine the utility of this technology for guiding proper patient treatment. For example, a study by the Southwest Oncology Group, is investigating a strategy of changing or maintaining therapy based on circulating tumor cell levels in patients with metastatic breast cancer. This trial might answer the question of whether changing treatment based on an elevated or increasing circulating tumor cell count alone is warranted.
In closing, this concludes our presentation on the use of the CellSearch System for the detection of circulating tumor cells in patients with metastatic cancer. We hope that this information has been useful. Thank you.
The Future of CTC |
Jump to section:
- Introduction
- Circulating Tumor Cell (CTC)
- The Metastatic Process
- Needle in a Haystack...
- Circulating Tumor Cells
- The CellSearch System (Veridex LLC)
- Automated Sample Preparation
- Labeling and Identification of CTCs
- Labeling and Identification of Cells
- Cell Analysis
- Mayo Medical Laboratories FDA-Cleared Assays
- Metastatic Breast Cancer (MBC)
- CellSearch Use in MBC Clinical Trial6
- Progression-Free Survival in MBC
- Overall Survival in MBC
- Metastatic Colorectal Cancer (MCRC)
- CellSearch Use in MCRC Clinical Trial8
- Progression-Free Survival in MCRC
- Overall Survival in MCRC
- Metastatic Prostate Cancer (MPC)
- CellSearch Use in MPC Clinical Trial8
- Progression-Free Survival in MPC
- Overall Survival in MPC
- The Future of CTC
- References
- Questions?
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