Circulating Tumor Cells and the CellSearch Assay

Metastatic Colorectal Cancer (MCRC)

April 2011

Now let's discuss the use of the CellSearch Assay for metastatic colorectal cancer.

In 2010, an estimated 142,000 new cases of colorectal cancer were diagnosed in the United States with approximately 51,000 deaths due to colorectal cancer. Of the new cases, nearly 20% had metastatic colorectal cancer when diagnosed and nearly one-third will develop metastases during clinical followup. Therefore, approximately 75,000 new patients are being treated for metastatic colorectal cancer every year.

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Metastatic Colorectal Cancer (MCRC)

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Jump to section:

• Introduction
• Circulating Tumor Cell (CTC)
• The Metastatic Process
• Needle in a Haystack...
• Circulating Tumor Cells
• The CellSearch System (Veridex LLC)
• Automated Sample Preparation
• Labeling and Identification of CTCs
• Labeling and Identification of Cells
• Cell Analysis
• Mayo Medical Laboratories FDA-Cleared Assays
• Metastatic Breast Cancer (MBC)
• CellSearch Use in MBC Clinical Trial⁶
• Progression-Free Survival in MBC
• Overall Survival in MBC
• Metastatic Colorectal Cancer (MCRC)
• CellSearch Use in MCRC Clinical Trial⁸
• Progression-Free Survival in MCRC
• Overall Survival in MCRC
• Metastatic Prostate Cancer (MPC)
• CellSearch Use in MPC Clinical Trial⁸
• Progression-Free Survival in MPC
• Overall Survival in MPC
• The Future of CTC
• References
• Questions?