Circulating Tumor Cells and the CellSearch Assay

Mayo Medical Laboratories FDA-Cleared Assays

April 2011

At Mayo Clinic we offer all 3 of the FDA approved tests for circulating tumor cells using the CellSearch platform. Test number 89089, is for circulating tumor cells in metastatic beast cancer. Test number 89162, is for circulating tumor cells in metastatic colorectal cancer. And finally, test number 60142, which is for circulating tumor cells in metastatic prostate cancer patients.

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FDA-Cleared Assays

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Jump to section:

• Introduction
• Circulating Tumor Cell (CTC)
• The Metastatic Process
• Needle in a Haystack...
• Circulating Tumor Cells
• The CellSearch System (Veridex LLC)
• Automated Sample Preparation
• Labeling and Identification of CTCs
• Labeling and Identification of Cells
• Cell Analysis
• Mayo Medical Laboratories FDA-Cleared Assays
• Metastatic Breast Cancer (MBC)
• CellSearch Use in MBC Clinical Trial⁶
• Progression-Free Survival in MBC
• Overall Survival in MBC
• Metastatic Colorectal Cancer (MCRC)
• CellSearch Use in MCRC Clinical Trial⁸
• Progression-Free Survival in MCRC
• Overall Survival in MCRC
• Metastatic Prostate Cancer (MPC)
• CellSearch Use in MPC Clinical Trial⁸
• Progression-Free Survival in MPC
• Overall Survival in MPC
• The Future of CTC
• References
• Questions?