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Circulating Tumor Cells and the CellSearch Assay



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Needle in a Haystack...

Slide 4

April 2011

Tumors shed an enormous number of tumor cells. It is estimated that approximately one million circulating tumor cells are shed per gram of tumor tissue. However, only a small proportion of these CTCs survive. Within 24 hours, less than 0.1% of these cells are still viable and less than 0.01% survive to produce metastases. Patients with metastatic cancer have been found to have approximately 1 tumor cell per 100,000 to 10 million mononuclear cells in their peripheral blood.

Needle in a Haystack...

 


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