Maternal Serum Screening
Down Syndrome, Trisomy 18 and Neural Tube Defects
Maternal Serum Screening: Options
March 2011
In this presentation, I will discuss 3 options for maternal serum screening. These options are first trimester, second trimester and sequential screening. Sequential screening is a type of cross-trimester screening which uses markers from the first and second trimester screening tests. Sequential screening was introduced to increase the detection rate and decrease the false-positive rate seen with the first 2 options.
It is important to keep in mind that these 3 options are screening tests. This means that a screen-negative result does not guarantee the absence of fetal defects and a screen-positive will need additional testing to determine if a defect is present.
Maternal Serum Screening: Options |
Jump to section:
- Introduction
- What is Maternal Serum Screening?
- Who Should Be Offered Maternal Serum Screening?
- Maternal Serum Screening: Options
- Maternal Serum Screening: Risk Calculation
- First Trimester Serum Screening
- Nuchal Translucency (NT)
- Nuchal Translucency (NT)
- Nuchal Translucency (NT)
- First Trimester Serum Screening
- First Trimester Screening
- Second Trimester Screening
- Second Trimester Screening
- Second Trimester Screening
- Sequential Screening
- Sequential Screening
- Sequential Screening
- Sequential Screening
- Mayo Medical Laboratories Maternal Serum Screening Options
- References
- Questions?


