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Monoclonal Gammopathy of Undetermined Significance (MGUS)


Slide 1

March 2011

Welcome to Mayo Medical Laboratories' Hot Topics. These presentations provide short discussions of current topics and may be helpful to you in your practice.

Our presenter for this program is Dr. Jerry Katzmann, from the Division of Clinical Biochemistry and Immunology at Mayo Clinic. Dr. Katzmann will discuss laboratory testing for monoclonal gammopathy of undetermined significance (MGUS) and clinical implications of this diagnosis.

Today I want to talk about monoclonal gammopathy of undetermined significance — sometimes shortened to "mugus" or "M-gus." Years ago this abnormality was called benign monoclonal gammopathy (or BMG), but as we'll see, this was a misnomer.

MGUS is by far the most common monoclonal gammopathy that is identified in the laboratory. It is therefore important for laboratorians to understand this disorder.



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