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Fungal Molecular Diagnostics

Meningeal Coccidioidomycosis Diagnosed by Real-Time PCR Analysis of Cerebrospinal Fluid5

Slide 29

February 2011

In the second study, we described 2 cases of coccidioides meningitis that were rapidly diagnosed using the real-time PCR assay. The PCR results were available several days before culture or serologic confirmation was achieved. Laboratory studies on spinal fluid (CSF) are often difficult due to the paucity of organism present in the specimen, but these 2 cases serve to highlight the potential utility of molecular methods in the diagnosis of meningeal coccidiomycosis.

Coccidioidomycosis Diagnosed by Cerebrospinal Fluid5


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