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Fungal Molecular Diagnostics


Currently Available Molecular Diagnostics for Fungi

Slide 6

February 2011

Currently there are a limited number of molecular diagnostic tests available for the detection and identification of fungi in the clinical laboratory. For fungal isolates growing in pure culture, nucleic acid hybridization probes, DNA sequencing, peptide nucleic acid fluorescence in situ hybridization (or PNA FISH) probes, and laboratory-developed polymerase chain reaction (or PCR) tests are available. Molecular methods used in the direct detection and identification of fungi from patient specimens are even further limited to a handful of laboratory-developed PCR tests targeting specific fungal agents. There are several diagnostics companies who have developed or who are developing PCR, array-based, and other molecular tests for fungi but, in large part, these have not yet entered into routine clinical laboratory use at this time.

Currently Available Fungi Diagnostics

 


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