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Autoimmune Gastrointestinal Dysmotility (AGID) Evaluation


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Clinical Utility

Slide 13

January 2011

So what are the appropriate clinical circumstances to do the autoimmune GI dysmotility serological evaluation? There are five specific uses for this testing. Firstly, this testing can be used for investigating acquired idiopathic gastrointestinal dysmotility to see if an idiopathic autoimmune or paraneoplastic basis can be established for this. This can then help direct treatment. If one or more of the antibodies described were detected, this may increase the clinician’s confidence that a trial of immunosuppression is warranted. Thirdly, the antibody profile detected can help predict the cancer type. Fourthly, this testing can be used to investigate GI dysmotility occurring during cancer therapy that was not explainable by recurrent cancer or metastasis.

Clinical Utility


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