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Autoimmune Gastrointestinal Dysmotility (AGID) Evaluation


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Antibody Profile

Slide 11

January 2011

On the next slide I am going to go through the profile and the different antibodies that are tested for. Before I do that, I am just going to briefly mention that there are 3 different types of antibodies tested for. First of all, the neuronal nuclear antibody such as ANNA-1 or antineuronal nuclear antibody type-1 which is known in the literature also as anti-hu antibody. As mentioned earlier this is associated with small cell carcinoma. Then there are another group of antibodies which have specificity for antigens in cytoplasm of nerve and muscle. These include CRMP-5, IgG, GAD-65 and striational antibody. Finally, the last group of antibodies are known as cation channel antibodies, which include ganglionic and muscle acetylcholine receptor antibodies, N type calcium channel antibody and the voltage-gated potassium channel antibody.

Antibody Profile


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