Autoimmune Gastrointestinal Dysmotility (AGID) Evaluation
Antibody Profile
January 2011
On the next slide I am going to go through the profile and the different antibodies that are tested for. Before I do that, I am just going to briefly mention that there are 3 different types of antibodies tested for. First of all, the neuronal nuclear antibody such as ANNA-1 or antineuronal nuclear antibody type-1 which is known in the literature also as anti-hu antibody. As mentioned earlier this is associated with small cell carcinoma. Then there are another group of antibodies which have specificity for antigens in cytoplasm of nerve and muscle. These include CRMP-5, IgG, GAD-65 and striational antibody. Finally, the last group of antibodies are known as cation channel antibodies, which include ganglionic and muscle acetylcholine receptor antibodies, N type calcium channel antibody and the voltage-gated potassium channel antibody.
Antibody Profile |
Jump to section:
- Introduction
- New Profile
- Autoimmune Gastrointestinal Dysmotility
- Symptoms
- Diagnosis1
- Autoimmune Gastrointestinal Dysmotility1,2
- Gastrointestinal Motility Studies
- Antibody Evaluation
- Ganglionic Acetylcholine Receptor (AChR) Autoantibody3,4
- Ganglionic Acetylcholine Receptor (AChR) Autoantibody
- Antibody Profile
- AGID Evaluation Testing Algorithm
- Clinical Utility
- Clinical Utility
- Summary
- References
- Questions?
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