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Paroxysmal Nocturnal Hemoglobinuria


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Role of Laboratory Testing

Slide 9

December 2010

There are 3 clinical scenarios in which laboratory testing for PNH is appropriate. First, patients with clinical suspicion of having classical PNH should undergo testing for diagnostic purposes. Second, patients with established PNH diagnosis should be monitored regularly, at 1 year intervals if stable, or more frequently, particularly if on therapy. Finally, patients with suspected myelodysplasia and aplastic anemia should undergo testing for detection of small clones; small clones in aplastic anemia should be followed regularly as these clones may progress into classical PNH.

Role of Laboratory Testing


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