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Paroxysmal Nocturnal Hemoglobinuria


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New Developments, cont.

Slide 8

December 2010

Second recent discovery is that small PNH clones can be detected in a significant number of patients with myelodysplastic syndrome and/or aplastic anemia. Although the significance of this finding is not firmly established, it appears that the presence of small PNH clones is associated with responsiveness to immunosuppressive therapy such as ATG and Cyclosporin A.

New Developments, cont.


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