Paroxysmal Nocturnal Hemoglobinuria
Prevalence
December 2010
PNH is a rare disease; there are about 4 to 6 thousand patients currently in the US, with the annual incidence of about 1.3 per million people. The reports on the overall 5 year mortality from the disease go as high as 35%. It is equally prevalent in men and women and affects all ages, median population being in their early 30s. PNH has a progressive course with episodes of complications and transfusion dependence, severely affecting patient's life.
Prevalence |
Jump to section:
- Introduction
- Paroxysmal Nocturnal Hemoglobinuria
- Prevalence
- Pathogenesis
- Paroxysmal Nocturnal Hemoglobinuria
- Progression
- New Developments
- New Developments, cont.
- Role of Laboratory Testing
- International PNH Group Recommendations: Who to Test?
- Diagnosis
- International PNH Group Recommendation: How to Test?
- Normal
- New WBC PNH
- Sensitivity and Reference Interval
- Interpretation and Reporting
- PNH—Summary
- Questions?
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