Common Test-Ordering Errors
Part 2: Misordered Tests

Indications for Ordering #88800

May 2010

Test #88800 should only be ordered if very detailed B-cell subset information is needed. Clinical examples of this include:

• Common variable immunodeficiency: a primary immunodeficiency with
  a prevalence of 1:25,000 to 1:50,000
• Hyper-IgM syndromes
• Assessing B-cell subset reconstitution after stem cell or bone marrow transplant
• Assessing response to B cell-depleting immunotherapy
  

In most other non-AIDS situations, “T- and B-Cell Quantitation by Flow Cytometry” is sufficient.

In the 3 examples that I just discussed, we are investigating T- or B-cell deficiencies (that is, situations with low cell counts).

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Indications for Ordering #88800

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Jump to section:

• Introduction
• Testing at Mayo Medical Laboratories
• Common MML Test-Ordering Errors
• Misordered Tests
• T- & B-Cell Tests by Flow Cytometry
• CD4 Count for Immune Monitoring, Blood (#84348)
• T- and B-Cell Quantitation by Flow Cytometry (#9336)
• B-Cell Phenotyping Profile for Immunodeficiency and Immune Competence Assessment, Blood (#88800)
• Indications for Ordering #88800
• Leukemia/Lymphoma Immunophenotyping (#3287)
• Conclusion
• Questions?