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Leukocyte Alkaline Phosphatase Stain (LAP)

Optimizing Laboratory Testing for Hematologic
Disorders Series

Alternatives to LAP

Slide 19

September 2010

What are testing alternatives to LAP?  Clearly, it depends on the clinical picture. If the patient has an unexplained elevation in counts and/or unexplained splenomegaly, then a myeloproliferative disorder will likely be considered in the differential diagnosis. If CML is a consideration, then BCR/ABL testing is the appropriate route, whereas if PV or other MPNs are in the differential, then JAK2 testing is required.

Alternatives to LAP


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