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Leukocyte Alkaline Phosphatase Stain (LAP)

Optimizing Laboratory Testing for Hematologic
Disorders Series



LAP: A Test Whose Time Has Passed

Slide 17

September 2010

To summarize why are we discontinuing the LAP:   First of all, a low LAP score is not specific for CML and can be found in patients with MPN, MDS, and even benign or reactive conditions. A high LAP score is not specific for PV and can be identified in patients with other MPNs, MDS, and numerous, benign, non-infectious conditions. Likewise, a high LAP score is not sensitive for PV as not all PV cases will have a high LAP score.

A Test Whose Time Has Passed

 


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