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Leukocyte Alkaline Phosphatase Stain (LAP)

Optimizing Laboratory Testing for Hematologic
Disorders Series



Low LAP Scores* Not Specific for CML: A Mayo 1-Year Experience

Slide 13

September 2010

The next four slides summarize a one-year experience that we had here looking at outcomes in patients who had LAPs ordered on Mayo Clinic patients. If we look at patients who had low LAP scores, there were a variety of myeloid malignancies that were associated with a low LAP. This included six cases of CML but a variety of MPN and MDS disorders were also identified with low LAP scores. This clearly points out the lack of specificity of a low LAP score for CML.

Low Scores* Not Specific for CML

 


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