Helicobacter pylori: Overview and Considerations for Diagnostic Testing

Types of Testing

August 2010

Diagnostics of Helicobacter pylori infection can be divided into 2 groups:

• Invasive; and
• Noninvasive testing

Let’s first discuss invasive testing, which is based on the use of endoscopy and employs Histology, Rapid Urease testing, and Culture.

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Types of Testing

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Jump to section:

• Introduction
• Overview
• Helicobacter pylori
• Helicobacter spp. History¹
• Epidemiology²
• Pathogenesis
• Diagnosis of Infection
• Testing
• Types of Testing
• Endoscopy
• Rapid Urease Test
• Culture
• Types of Testing
• Urea Breath Test
• Urea Breath Test Limitations
• Serology - IgM and IgA ELISA³
• Serology: IgG ELFA
• Serology
• Serology Limitations
• Fecal Antigen Test EIA
• "Test of Cure"
• Algorithm
• Conclusions
• Tests Available From Mayo Medical Laboratories
• References
• Questions?