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Helicobacter pylori: Overview and Considerations for Diagnostic Testing



Pathogenesis

Slide 6

August 2010

As first demonstrated by Dr. Marshall’s work, exposure to an infectious dose of Helicobacter pylori can result in an acute gastritis, with abdominal pain, nausea, and vomiting within 2 weeks of exposure.This can progress to chronic gastritis, with concomitant duodenal inflammation and development of gastric ulcers. Persistent inflammation due to Helicobacter pylori infection is considered a risk factor for eventual development of gastric adenocarcinoma.

Pathogenesis

 


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