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Helicobacter pylori: Overview and Considerations for Diagnostic Testing


Slide 23

August 2010

So, to summarize today’s discussion:

Helicobacter pylori affects 30% to 40% of the US population, but prevalence in most US communities may be closer to 20%.

The approach of test and treat if the patient is symptomatic is strongly recommended. If alarm features are present, endoscopy with histology and rapid urease testing should be performed.

In patients with dysphagia, or other pertinent clinical indications, noninvasive tests such as the urea breath test or fecal antigen test are the preferred approach. These tests cannot be used during treatment; they can be used 4 weeks after completion of treatment.

Serology can be used to detect acute infections, and can be used during treatment, but overall sensitivity and specificity are much lower than the urea breath test and fecal antigen tests. Serology cannot be used to assess Helicobacter pylori eradication.

This concludes today’s discussion of Helicobacter pylori and considerations for diagnostic testing.



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