Helicobacter pylori: Overview and Considerations for Diagnostic Testing

Algorithm

August 2010

Here is an algorithm located at the link indicated on the slide that summarizes the types and best usage of tests for detection of Helicobacter pylori that we have discussed today.

Please note:

• Histology with special staining for Helicobacter pylori organisms, combined with the urea breath test, stool antigen and/or culture are the gold standard tests for diagnosis with associated high sensitivity and specificity.
• Culture is not routinely used for initial diagnosis. Culture is required for antibiotic susceptibility testing if the physician suspects antibiotic resistance in patients who have previously failed therapy.
• Due to low specificity, confirmation of positive serology (especially IgG) by either fecal antigen testing or urea breath testing should be considered.

< Previous Slide

Algorithm

Next Slide >

 

Jump to section:

• Introduction
• Overview
• Helicobacter pylori
• Helicobacter spp. History¹
• Epidemiology²
• Pathogenesis
• Diagnosis of Infection
• Testing
• Types of Testing
• Endoscopy
• Rapid Urease Test
• Culture
• Types of Testing
• Urea Breath Test
• Urea Breath Test Limitations
• Serology - IgM and IgA ELISA³
• Serology: IgG ELFA
• Serology
• Serology Limitations
• Fecal Antigen Test EIA
• "Test of Cure"
• Algorithm
• Conclusions
• Tests Available From Mayo Medical Laboratories
• References
• Questions?