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Laboratory Diagnosis of Tick-Borne Infections

Part 2


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Advantages and Limitations of Conventional Tests

Slide 4

July 2010

There are both advantages and limitations to conventional tests for these diseases.

First of all, these tests have been in use for a long time, so they are familiar, proven to provide utility in certain situations, and they are widely available in clinical laboratories. Therefore, they are used in diagnostic algorithms published by nationally and internationally recommended committees and professional societies.

However, subjective morphologic interpretation requires experience, such as interpretation of blood smears, and formation of antibody response for serologic tests typically takes 4 to 6 weeks following exposure. Finally, cross-reactivity and nonspecific serologic responses are common and may be misleading.

Advantages and Limitations of Conventional Tests


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