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Laboratory Diagnosis of Tick-Borne Infections

Part 2



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Serologic Assay: Test of Choice for Diagnosis of Lyme Disease

Slide 26

July 2010

Now, as Dr. Binnicker discussed, serological assays are the test of choice for Lyme disease, and are typically performed in a tiered approach, starting with a screening enzyme immunoassay or EIA. However, as shown in this chart, the sensitivity of the EIA is dependent on the stage of disease. And notice that in stage 1 or localized disease, the sensitivity of the EIA is only 74%.

Test of Choice for Diagnosis of Lyme Disease

 


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