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Laboratory Diagnosis of Tick-Borne Infections

Part 1


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Lyme Disease - Factors to Consider

Slide 32

July 2010

The laboratory diagnosis of Lyme disease is most commonly achieved by serologic testing, which should be limited to those persons with an appropriate exposure history and objective clinical findings. When serology is ordered, testing should be performed using the 2-step approach as recommended by the CDC, in which specimens are first tested by a highly sensitive screening method, such as EIA, with all screen-positive or equivocal specimens being tested by Western blot. And finally, the results of Lyme serology should be used to support a clinical diagnosis in those patients being evaluated for Lyme disease.

Lyme Disease - Factors to Consider


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