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Laboratory Diagnosis of Tick-Borne Infections

Part 1



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Lyme Disease - Serologic Assays

Slide 27

July 2010

Lyme Western blot assays test for IgM and IgG-class antibodies to Borrelia burgdorferi.

Western blot should be considered a supplementary serologic approach, and not confirmatory, due to the potential for false positives and inter- and intra-laboratory result variability with this method. And as we’ve discussed, the results of Western blot should be interpreted according to the current CDC criteria, and testing by Western blot is not recommended in those patients testing negative by screen EIA.

Lyme Disease - Serologic Assays

 


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