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Laboratory Diagnosis of Tick-Borne Infections

Part 1


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Conventional Methods for Diagnosis of Lyme Disease

Slide 23

July 2010

When laboratory testing is performed, there are several standard methods that can be used. The first is culture, with the optimal specimens including tissue obtained by biopsy of the EM rash, or synovial fluid collected from an affected joint. Although a positive culture for Borrelia burgdorferi is diagnostic, recovery of this organism in culturemay take from 4 days to several weeks, and culture is usually performed only at specialized, reference or government health department laboratories.

The most common approach for the laboratory diagnosis of Lyme disease is through the use of serology, in which methods such as enzyme immunoassay or Western blot are often performed.

Conventional Methods for Diagnosis of Lyme Disease


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