Laboratory Diagnosis of Tick-Borne Infections

Conventional Methods for Diagnosis of Babesia

July 2010

There are several distinguishing features that can help in differentiating Babesia and Plasmodium when examining thin blood smears. These include the fact that Babesia trophozoites are variable in size, ranging from 1 to 5 microns. Second, multiply infected erythrocytes are more common in Babesiosis. And finally, when tetrads of merozoites, also known as the maltese cross form, are seen, this is pathognomonic for Babesia. However, this is infrequently observed.

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Conventional Methods for Diagnosis of Babesia

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• Introduction
• Outline
• Patient Case 1
• Laboratory Workup
• Conventional Methods for Diagnosis of Ehrlichiosis and Anaplasmosis
• Conventional Methods for Diagnosis of Ehrlichiosis and Anaplasmosis
• Conventional Methods for Diagnosis of Ehrlichiosis and Anaplasmosis
• Typical Positive Result by IFA
• Conventional Methods for Diagnosis of Ehrlichiosis and Anaplasmosis
• Diagnostic Tests for HME and HGA
• Conventional Methods for Diagnosis of Ehrlichiosis and Anaplasmosis
• Conventional Methods for Diagnosis of Ehrlichiosis and Anaplasmosis
• Patient Case 2
• Giemsa-stained Preparation Slide
• Giemsa-stained Preparation Slide
• Conventional Methods for Diagnosis of Babesia
• Conventional Methods for Diagnosis of Babesia
• Conventional Methods for Diagnosis of Babesia
• Conventional Methods for Diagnosis of Babesia
• Conventional Methods for Diagnosis of Babesia
• Patient Case 3
• Lyme Disease - Diagnostic Approach
• Conventional Methods for Diagnosis of Lyme Disease
• Patient Case 3 (continued)
• Diagnosis of Lyme Disease
• Lyme Disease - Serologic Assays
• Lyme Disease - Serologic Assays
• Lyme Disease - Serologic Assays
• Patient Case 3 (continued)
• Lyme Disease - Serologic Assays
• Patient Case 3 (continued)
• Lyme Disease - Factors to Consider
• Conclusions
• References
• Questions?